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Mucosal Transmission of Human Immunodeficiency Virus
Denis M. Tebit, Nicaise Ndembi, Aaron Weinberg, and Miguel E. Quiñones-Mateu
Curr HIV Res. 2012 January 1; 10(1): 3–8 PMCID: PMC3744389 NIHMSID: NIHMS498042

Mucosal HIV Transmission
Tebit D, Ndembi N, Weinberg A, Quinones-Mateu ME
2011. Current HIV Research (in press)

Systems immunology and adaptive immune response to HIV infection
Yohannes E, Chance MR
Encyclopedia of Systems Biology, W. Dubitzky, O. Wolkenhauer, K. Cho & H. Yokota (eds.),
DOI 10.1007/978-1-4419-9863-7, 2011

The Toll-like Receptor 1/2 agonists Pam(3)CSK(4) and Human Beta Defensin-3 differentially induce IL-10 and NF-kB signaling patterns in human monocytes
Funderburg NT, Jadlowsky JK, Lederman MM, Feng Z, Weinberg A, Sieg SF
Immunology 2011 Oct;134(2):151-60. doi:10.1111/j.1365-2567/2-11/-3475x/ PMID: 21896010 PMCID: PMC3194223

An Antimicrobial Peptide Regulates Tumor-Associated Macrophage Trafficking via the Chemokine Receptor CCR2, a Model for Tumorigenesis
Jin G, Kawsar HI, Hirsch SA, Zeng C, Jia X, Feng Z, Ghosh SK, Zheng QY, Zhou A, McIntyre TM, Weinberg A.
PLoS ONE. 2010 Jun 8;5(6):e10993. doi:10.137/journal.pone.0010993 PMID: 20544025 PMCID: PMC2882331

Innate Immunity and Oral Carcinogenesis
Jin G, Hirsch SA, Weinberg A.
In Oral Cancer: Causes, Diagnosis and Treatment Chapter X. Editor: Michael K. Harris
Nova Science Publishers, Inc. pp253-270 (2011). ISBN: 978-1-61209-305-5

Epithelial Cell-Derived Antimicrobial Peptides Are Multifunctional Agents That Bridge Innate and Adaptive Immunity
McCormick TS, Weinberg A
Periodontol 2000. 2010 Oct;54(1): 195-206. PMID:20712640

Proteomic Signatures of Human Oral Epithelial Cells in HIV-infected Subjects
Elizabeth Yohannes, Santosh K. Ghosh, Bin Jiang, Thomas S. McCormick, Aaron Weinberg, Edward Hill, Faddy Faddoul, Mark R. Chance
PLoS1, 2011 (in press)

The Oral HIV/AIDS Research Alliance: Updated Case Definitions of Oral Disease Endpoints
Shiboski CH, Patton LL, Webster-Cyriaque JY, Greenspan D, Traboulsi RS, Ghannoum M, Jurevic R, Phelan JA, Reznik D, Greenspan JS, Oral HIV/AIDS Research Alliance; AIDS Clinical Trial Group Network.
J Oral Path Med. 2009; 38:481-8. PMID: 19594839

Characterization of the Oral Fungal Microbiome (Mycobiome) in Healthy Individuals
Ghannoum MA, Jurevic RJ, Mukherjee PK, Cui F, Sikaroodi M, Naqvi A, Gillevet PM.
PLoS Pathog. 2010 Jan 8;6(1):e1000713. PMCID: PMC2795202

Metabolomics Reveals Differential Levels of Oral Metabolites in HIV-Infected Patients
Ghannoum M, Muhkerjee P, Jurevic R, Retuerto M, Brown R, Sikaroodi M, Webster-Cyriaque J, and Gillevet P
Omics, 2011, Vol 15, # E pub. PMID:21751871

Chemokine (C-C Motif) Receptor 5 22459 Genotype in Patients Receiving Highly Active Antiretroviral Therapy: Race-Specific Influence on Virologic Success
Mehlotra RK, Cheruvu VK, Zikursh M, Benish RL, Lederman MM, Salata RA, Gripshover B, McComsey GA, Lisgaris MV, Fulton S, Subauste CS, Jurevic RJ, Guillemette C, Zimmerman PA, Rodriguez B.
Journal of Infectious Diseases 2011:204 291-298. PMID:21673041

Worldwide variation in Human drug-metabolism enzyme genes CYP2B6 and UGT 2B7: implication for HIV/AIDS treatment
Jing Li, Vincent Menard, Rebekah Benish, Richard Jurevic, Chantal Guillemette, Mark Stoneking, Peter Zimmerman, and Rajeev Mehlotra
Pharmacogenomics, (In Press) Online open access ahead of print available March 2012.

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Career Openings

A postdoctoral position is available to work in the area of oral innate immunity, including studies to decipher how epithelial cell derived antimicrobial peptides (AMPs) induce G-protein coupled receptor antagonism in adaptive immune cells and the trafficking of AMPs within these cells. The qualified candidate must be trained in molecular biology techniques, PCR assays, transfections, transductions, RNA interference and with some knowledge of protein chemistry and tissue culture. Additional experience in immunology is desired.

Candidates must have earned their PhDs within the last 1-2 years. The opportunity for further advancement within the institution exists. Applicants should submit an updated CV, three references, and a cover letter describing their research goals and interests to: Dr. Aaron Weinberg, Chair, Department of Biological Sciences, Case Western Reserve University School of Dental Medicine, 10900 Euclid Ave., Cleveland, OH 44106-4905 or by email: aaron.weinberg@case.edu.

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Research in the Case School of Dental Medicine

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