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Regulation

Epigenetic Regulation of Viral Replication by Periodontal Bacteria

Sponsored by CWRU Center for AIDS Research Developmental Pilot Program
Project Period: May 1, 2013 - April 30, 2014

Abstract

This pilot project studies the mechanisms by which periodontal pathogens promote replication of HIV and herpesviruses in the oral cavity of HIV patients. More specifically, we investigate how short chain fatty acids from oral bacteria modulate cellular epigenetic regulatory machinery to induce viral gene expression and replication.

Project Team

Fengchun Ye – Department of Biological Sciences

Dr. Fengchun Ye
Dr. Fengchun Ye
Principal Investigator